Download Files:

Canertinib

SKU T6136-5 mg Category Small Compound Brand: TargetMol

Price range: 50 CAD through 126 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

10 mg 25 mg 5 mg 50 mg

Clear

Products Details

Product Description

– Canertinib (CI-1033) is a pan-erbB tyrosine kinase inhibitor which work against esophageal squamous cell carcinoma in vitro and in vivo. Canertinib treatment significantly affects tumour metabolism, proliferation and hypoxia as determined by PET.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T6136

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C24H25ClFN5O3

Citations

– 1. Jin X, Yang Y, Liu D, et al.Identification of a covalent NEK7 inhibitor to alleviate NLRP3 inflammasome-driven metainflammation.Cell Communication and Signaling.2024, 22(1): 565.

References

– Smaill JB et al. J Med Chem. 2000; 43(7): 1380-1397.

CAS Number

– 267243-28-7

Molecular Weight

– C24H25ClFN5O3

Compound Purity

– 0.9983

SMILES

– Fc1ccc(Nc2ncnc3cc(OCCCN4CCOCC4)c(NC(=O)C=C)cc23)cc1Cl

Pathway

– Tyrosine Kinase/Adaptors|||Angiogenesis|||JAK/STAT signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.