Pralatrexate

SKU T6120-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 48 CAD through 590 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Products Details

Product Description

– Pralatrexate (10-Propargyl-10-deazaaminopterin) is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive activities.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T6120

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H23N7O5

References

– Marchi E, et al. Clin Cancer Res, 2010, 16(14), 3648-3658.

CAS Number

– 146464-95-1

Molecular Weight

– C23H23N7O5

Compound Purity

– 0.9959

SMILES

– Nc1nc(N)c2nc(CC(CC#C)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cnc2n1

Pathway

– Cell Cycle/Checkpoint|||Metabolism|||Apoptosis|||Tyrosine Kinase/Adaptors|||DNA Damage/DNA Repair

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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For Research Use Only. All Immunomart products are sold strictly for laboratory research use only (RUO). Not for human or veterinary consumption, therapeutic, or diagnostic use.