Download Files:

UCB-5307

SKU T61111-1 mg Category Small Compound Brand: TargetMol

Price range: 82 CAD through 3,008 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 10 mg 100 mg 25 mg 5 mg 50 mg 500 mg

Clear

Products Details

Product Description

– UCB-5307 is a small molecule compound that inhibits TNFR1 signal transduction and downstream function in vitro. The KD of human TNFα is 9 nM. The TNF was directly bound by slow binding kinetics,KD= 6 nM. UCB-5307 can pass through prefabricated hTNF/hTNFR1 complexes.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T61111

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H21N3O

References

– O’Connell J, et al. Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer. Nat Commun. 2019;10(1):5795.

CAS Number

– 1515887-44-1

Molecular Weight

– C22H21N3O

Compound Purity

– 0.9802

SMILES

– Cc1ccc(C)c(Cn2c(nc3ccccc23)C(O)c2ccncc2)c1

Pathway

– Apoptosis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.