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NVP-AEW541

SKU T6080-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 58 CAD through 458 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 25 mg 5 mg

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Products Details

Product Description

– NVP-AEW541 (AEW541), a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and specificity for IGF-1R in a cell-based assay.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T6080

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C27H29N5O

Citations

– 1. Lin W, Niu R, Park S M, et al.IGFBP5 is an ROR1 ligand promoting glioblastoma invasion via ROR1/HER2-CREB signaling axis.Nature Communications.2023, 14(1): 1578.

References

– García-Echeverría C, et al. Cancer Cell. 2004, 5(3), 231-239.

CAS Number

– 475489-16-8

Molecular Weight

– C27H29N5O

Compound Purity

– 0.9955

SMILES

– Nc1ncnc2n(cc(-c3cccc(OCc4ccccc4)c3)c12)C1CC(CN2CCC2)C1

Pathway

– Angiogenesis|||Tyrosine Kinase/Adaptors|||Autophagy

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.