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LCS3
Price range: 82 CAD through 3,072 CAD
Products Details
Product Description
– LCS3 is a reversible and non-competitive synergistic inhibitor of glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) with IC50s of 3.3 μM and 3.8 μM, respectively. LCS3 has antitumour activity, induces apoptosis and can be used in the study of lung adenocarcinoma (LUAD).
Web ID
– T60446
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C11H7ClN2O4
References
– Johnson FD, et al. Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells. Cell Rep. 2022 ; 38(6):110343.
CAS Number
– 109844-92-0
Molecular Weight
– C11H7ClN2O4
Compound Purity
– 0.9968
SMILES
– [O-][N+](=O)C1=CC=C(O1)C(=O)NC1=CC=C(Cl)C=C1
Pathway
– Apoptosis|||Oxidation-Reduction
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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