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(-)-Blebbistatin

SKU T6038-2 mg Category Small Compound Brand: TargetMol

Price range: 56 CAD through 765 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– (-)-Blebbistatin ((S)-(-)-Blebbistatin) is an S enantiomer of blebbistatin. It is a potent and selective myosin II inhibitor with IC50 ranging from 0.5 to 5 μM.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T6038

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H16N2O2

Citations

– 1. Sahara S, Ueno A, Wakita N, et al.(S)-(-)-blebbistatin O-benzoate has the potential to improve atopic dermatitis symptoms in NC/Nga mice by upregulating epidermal barrier function and inhibiting type 2 alarmin cytokine induction.PloS one.2024, 19(5): e0302781.

References

– Liu Z, et al. Blebbistatin inhibits contraction and accelerates migration in mouse hepatic stellate cells. Br J Pharmacol. 2010 Jan 1;159(2):304-15.

CAS Number

– 856925-71-8

Molecular Weight

– C18H16N2O2

Compound Purity

– 0.9961

SMILES

– Cc1ccc2N=C3N(CC[C@@]3(O)C(=O)c2c1)c1ccccc1

Pathway

– Cytoskeletal Signaling|||Membrane transporter/Ion channel

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.