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HS-243

SKU T60012-1 mg Category Small Compound Brand: TargetMol

Price range: 77 CAD through 1,349 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T60012

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H16N4O3

References

– Scarneo SA, et al. A highly selective inhibitor of interleukin-1 receptor-associated kinases 1/4 (IRAK-1/4) delineates the distinct signaling roles of IRAK-1/4 and the TAK1 kinase. J Biol Chem. 2020 Feb 7;295(6):1565-1574.

CAS Number

– 848249-10-5

Molecular Weight

– C17H16N4O3

Compound Purity

– 0.9734

SMILES

– CCCn1c(NC(=O)c2cccc(c2)[N+]([O-])=O)nc2ccccc12

Pathway

– Immunology/Inflammation|||Cell Cycle/Checkpoint|||NF-κB|||MAPK

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.