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Atractylenolide II

SKU T5S0168-1 mL * 10 mM (in DMSO) Category Natural Product Brand: TargetMol

Price range: 53 CAD through 795 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– 1. Atractylenolide II (2-Atractylenolide) has antimelanoma effect by inhibiting STAT3 signalling. 2. Atractylenolide II has cytotoxic/apoptotic effects may via p38 activation, ERK and Akt inactivation, p53 dependent.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T5S0168

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H20O2

Citations

– 1. Wang F, Li Z, Chen L, et al. Inhibition of ASCT2 induces hepatic stellate cell senescence with modified proinflammatory secretome through an IL-1α/NF-κB feedback pathway to inhibit liver fibrosis. Acta Pharmaceutica Sinica B. 2022 2. Cao L, Xu E, Zheng R, et al. Traditional Chinese medicine Lingguizhugan decoction ameliorate HFD-induced hepatic-lipid deposition in mice by inhibiting STING-mediated inflammation in macrophages. Chinese Medicine. 2022, 17(1): 1-16.

References

– Fu X Q , Chou G X , Kwan H Y , et al. Inhibition of STAT3 signalling contributes to the antimelanoma action of atractylenolide II[J]. Experimental Dermatology, 2014, 23(11):855-857.

CAS Number

– 73069-14-4

Molecular Weight

– C15H20O2

Compound Purity

– 0.9993

SMILES

– CC1=C2C[C@H]3C(=C)CCC[C@]3(C)C[C@@H]2OC1=O

Pathway

– MAPK|||Cytoskeletal Signaling|||JAK/STAT signaling|||PI3K/Akt/mTOR signaling|||Apoptosis|||Stem Cells

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.