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Atractylenolide I

SKU T5S0167-1 mL * 10 mM (in DMSO) Category Natural Product Brand: TargetMol

Price range: 58 CAD through 997 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– 1. Atractylenolide-I has an anti-inflammatory effect by inhibiting TNF-α and IL-6 production; ameliorates sepsis syndrome, liver and kidney functions by reduction of pro-inflammatory cytokines and LPS. 2. Atractylenolide-I significantly sensitizes the response of MyD88(+) EOC cells to paclitaxel by blocking MD-2-mediated TLR4/MyD88 signaling.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T5S0167

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H18O2

Citations

– 1. Wang F, Li Z, Chen L, et al. Inhibition of ASCT2 induces hepatic stellate cell senescence with modified proinflammatory secretome through an IL-1α/NF-κB feedback pathway to inhibit liver fibrosis. Acta Pharmaceutica Sinica B. 2022 2. Yu Z, Niu P, Su Z, et al.Role of Atractylenolide I in Cerebral Ischemia Reperfusion Injury.Revista Brasileira de Farmacognosia.2023: 1-10.

References

– Ji G , Chen R , Zheng J . Atractylenolide I inhibits lipopolysaccharide-induced inflammatory responses via mitogen-activated protein kinase pathways in RAW264.7 cells[J]. Immunopharmacology and Immunotoxicology, 2014, 36(6):420-425.

CAS Number

– 73069-13-3

Molecular Weight

– C15H18O2

Compound Purity

– 0.9755

SMILES

– CC1=C2C[C@H]3C(=C)CCC[C@]3(C)C=C2OC1=O

Pathway

– JAK/STAT signaling|||Angiogenesis|||Apoptosis|||Immunology/Inflammation|||Stem Cells|||Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.