NG25
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NG25

SKU T5643-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 126 CAD through 3,168 CAD

Products Details

Product Description

– NG25 is a potent dual inhibitor of TAK1 and MAP4K2, with IC50s of 149 nM and 21.7 nM, respectively.

Web ID

– T5643

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C29H30F3N5O2

Citations

– 1. Fan S, Huang X, Tong H, et al. p-TAK1 acts as a switch between myoblast proliferation phase and differentiation phase in mdx mice via regulating HO-1 expression. European Journal of Pharmacology. 2022: 175277.

References

– Wang Z , Zhang H , Shi M , et al. TAK1 inhibitor NG25 enhances doxorubicin-mediated apoptosis in breast cancer cells[J]. Scientific Reports, 2016, 6:32737.

CAS Number

– 1315355-93-1

Molecular Weight

– C29H30F3N5O2

Compound Purity

– 0.9832

SMILES

– CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(Oc4ccnc5[nH]ccc45)c3)cc2C(F)(F)F)CC1

Pathway

– MAPK

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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