Download Files:

IDF-11774

SKU T5537-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 88 CAD through 1,141 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

Clear

Products Details

Product Description

– IDF-11774 is a HIF-1 inhibitor.It reduces hif-1α HRE luciferase activity (IC50 = 3.65 μM).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T5537

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H32N2O2

Citations

– 1. Chang L L, Lu P H, Yang W, et al. AKR1C1 promotes non-small cell lung cancer proliferation via crosstalk between HIF-1α and metabolic reprogramming. Translational Oncology. 2022, 20: 101421

References

– Ban H S , Kim B K , Lee H , et al. The novel hypoxia-inducible factor-1α inhibitor IDF-11774 regulates cancer metabolism, thereby suppressing tumor growth[J]. Cell Death and Disease, 2017, 8(6):e2843.

CAS Number

– 1429054-28-3

Molecular Weight

– C23H32N2O2

Compound Purity

– 0.9805

SMILES

– CN1CCN(CC1)C(=O)COc1ccc(cc1)C12CC3CC(CC(C3)C1)C2

Pathway

– Angiogenesis|||Chromatin/Epigenetic|||Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.