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Prostaglandin E2

SKU T5014-1 mL * 10 mM (in DMSO) Category Natural Product Brand: TargetMol

Price range: 48 CAD through 869 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

2 mg 1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– Prostaglandin E2 (PGE2) is a naturally occurring hormone involved in various physiological processes, such as smooth muscle contraction and relaxation, vasodilation and constriction, blood pressure regulation, and inflammatory regulation.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T5014

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H32O5

Citations

– 1. Wang M, Wang X, Jiang B, et al. Identification of MRAP protein family as broad‐spectrum GPCR modulators. Clinical and Translational Medicine. 2022, 12(11): e1091. 2. Tang C, Sun H, Kadoki M, et al.Blocking Dectin-1 prevents colorectal tumorigenesis by suppressing prostaglandin E2 production in myeloid-derived suppressor cells and enhancing IL-22 binding protein expression.Nature Communications.2023, 14(1): 1493. 3. Chen S, Wu Y, Gao Y, et al.Allosterically inhibited PFKL via prostaglandin E2 withholds glucose metabolism and ovarian cancer invasiveness.Cell Reports.2023, 42(10): 113246. 4. Zhao M, Wu J, Jin Y, et al.Schisandrin B from Schisandra chinensis alleviated pain via glycine receptors, Nav1. 7 channels and Cav2. 2 channels.Journal of Ethnopharmacology.2024: 117996. 5. Xiang X, Wang K, Zhang H, et al.Blocking CX3CR1+ Tumor-associated Macrophages Enhances the Efficacy of Anti-PD-1 Therapy in Hepatocellular Carcinoma.Cancer Immunology Research.2024

References

– Buchanan FG, et al. Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor. J Biol Chem. 2003 Sep 12;278(37):35451-7.

CAS Number

– 363-24-6

Molecular Weight

– C20H32O5

Compound Purity

– 0.9994

SMILES

– CCCCC[C@H](O)C=C[C@H]1[C@H](O)CC(=O)[C@@H]1CC=C/CCCC(O)=O

Pathway

– Metabolism

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.