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Hinokiflavone

SKU T4S0181-1 mg Category Natural Product Brand: TargetMol

Price range: 62 CAD through 670 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

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Products Details

Product Description

– Hinokiflavone, a novel modulator of pre-mRNA splicing activity both in vitro and in cellulo, inhibits the assembly of the spliceosome, particularly blocking the formation of the B complex. Additionally, it acts as a SUMO protease inhibitor by impeding the activity of sentrin-specific protease 1 (SENP1). Hinokiflavone also demonstrates significant cytotoxicity, including the inhibition of MMP-9.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T4S0181

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C30H18O10

Citations

– 1. Xiao Y, Cai G P, Feng X, et al.Splicing factor YBX1 regulates bone marrow stromal cell fate during aging.The EMBO Journal.2023: e111762.

References

– Huang W , Liu C , Liu F , et al. Hinokiflavone induces apoptosis and inhibits migration of breast cancer cells via EMT signalling pathway[J]. Cell Biochemistry and Function, 2020, 38(11).

CAS Number

– 19202-36-9

Molecular Weight

– C30H18O10

Compound Purity

– 0.9867

SMILES

– Oc1ccc(cc1)-c1cc(=O)c2c(O)c(Oc3ccc(cc3)-c3cc(=O)c4c(O)cc(O)cc4o3)c(O)cc2o1

Pathway

– Apoptosis|||Proteases/Proteasome|||Ubiquitination

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.