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Takinib

SKU T4264-5 mg Category Small Compound Brand: TargetMol

Price range: 106 CAD through 552 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– Takinib (EDHS-206) is a specific and effective TAK1 inhibitor(IC50= 9.5 nM).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T4264

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H18N4O2

Citations

– 1. Da Q, Yan Z, Li Z, et al. TAK1 is involved in sodium L-lactate-stimulated p38 signaling and promotes apoptosis. Molecular and Cellular Biochemistry. 2020: 1-10

References

– Totzke J, et al. Takinib, a Selective TAK1 Inhibitor, Broadens the Therapeutic Efficacy of TNF-α Inhibition for Cancer and Autoimmune Disease. Cell Chem Biol. 2017 Aug 17;24(8):1029-1039.

CAS Number

– 1111556-37-6

Molecular Weight

– C18H18N4O2

Compound Purity

– 0.9829

SMILES

– CCCn1c(NC(=O)c2cccc(c2)C(N)=O)nc2ccccc12

Pathway

– Apoptosis|||MAPK

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.