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Streptomycin
$50 – $55
Products Details
Product Description
– Streptomycin (Agrept) is an effective antibiotic against M. tuberculosis, is used for the research of tuberculosis (TB). Streptomycin also is a bacteriocidal agent that can be used for the research of a number of bacterial infections. Streptomycin can bind strongly to nucleic acids, interferes and blocks protein synthesis while permitting continued RNA and DNA synthesis. Streptomycin, as a common antibiotic used in culture media, also is a blocker of stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes [1][2][3].
Web ID
– HY-B1906
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C21H39N7O12
Citations
– APL Bioeng. 2022, 6(4): 046106.|BMC Cancer. 2023 Mar 14;23(1):241.|Cancers (Basel). 2022 Sep 28;14(19):4740.|Food Chem. 2022 Sep 26;403:134399.|Free Radic Biol Med. 2023 Apr 10;S0891-5849(23)00373-8.|Genome Biol. 2023 Apr 30;24(1):98.|J Orthop Surg Res. 2022 Oct 28;17(1):468.|ACS Chem Biol. 2021 Dec 15.|ACS Omega. 2020 Nov 15;5(46):29935-29942.|Autophagy. 2021 Jul 20;1-19.|Dis Model Mech. 2021 Oct 13;dmm.049145.|Drug Dev Res. 2021 Aug 17.|Life Sci. 2020 Nov 15;261:118473.|Mol Med Rep. 2021 Dec;24(6):832.|Mol Med Rep. 2021 Dec;24(6):843.|PLoS One. 2020 Sep 3;15(9):e0235824.
References
– [1]J DAVIES, et al. STREPTOMYCIN, SUPPRESSION, AND THE CODE. Proc Natl Acad Sci U S A. 1964 May;51(5):883-90.|[2]Deisy M G C Rocha, et al. The Neglected Contribution of Streptomycin to the Tuberculosis Drug Resistance Problem. Genes (Basel). 2021 Dec 17;12(12):2003.|[3]Mandeep Singh, et al. Streptomycin sulphate loaded solid lipid nanoparticles show enhanced uptake in macrophage, lower MIC in Mycobacterium and improved oral bioavailability. Eur J Pharm Biopharm. 2021 Mar;160:100-124.
CAS Number
– 57-92-1
Molecular Weight
– 581.57
Compound Purity
– 99.88
SMILES
– N=C(N)N[C@@H]([C@@H]([C@H]([C@@H]([C@H]1O)O)NC(N)=N)O)[C@H]1O[C@H](O[C@H]([C@]2(O)C=O)C)[C@@H]2O[C@H]3[C@H]([C@@H]([C@H]([C@@H](O3)CO)O)O)NC
Clinical Information
– Launched
Research Area
– Infection; Neurological Disease
Solubility
– H2O : 125 mg/mL (ultrasonic)
Target
– Antibiotic;Bacterial
Isoform
– Aminoglycoside
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
