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5-Hydroxymethyl-2′-deoxycytidine

SKU T40834-1 mL * 10 mM (in DMSO) Category Natural Product Brand: TargetMol

Price range: 54 CAD through 1,744 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg 500 mg

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Products Details

Product Description

– 5-Hydroxymethyl-2′-deoxycytidine is an oxidized derivative of 5-methyl-2′-deoxycytidine (5-mdC) in DNA, causing DNA damage reactions, chromosomal aberrations, replication fork damage, and loss of cell viability.5-Hydroxymethyl-2′-deoxycytidine is an oxidized derivative of 5-methyl-2′-deoxycytidine in DNA. Hydroxymethyl-2′-deoxycytidine replication fork instability is associated with the presence of poly(ADP-ribose) polymerase 1 (PARP1) on chromatin.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T40834

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C10H15N3O5

References

– Ewelina Zarakowska, et al. Oxidation Products of 5-Methylcytosine are Decreased in Senescent Cells and Tissues of Progeroid Mice. J Gerontol A Biol Sci Med Sci. 2018 Jul 9;73(8):1003-1009.

CAS Number

– 7226-77-9

Molecular Weight

– C10H15N3O5

Compound Purity

– 0.998

SMILES

– Nc1nc(=O)n(cc1CO)[C@H]1C[C@H](O)[C@@H](CO)O1

Pathway

– Chromatin/Epigenetic|||DNA Damage/DNA Repair

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.