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ML-60218

SKU T40661-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 77 CAD through 1,952 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– ML-60218 is an inhibitor of broad-spectrum RNA pol III with IC50s of 32 and 27 μM for Saccharomyces cerevisiae and human. ML-60218 disrupts already assembled viroplasms and hampers the formation of new viroplasms.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T40661

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H15Cl2N3O2S2

Citations

– 1. Wei W, Zhang S, Han H, et al.NAT10-mediated ac4C tRNA modification promotes EGFR mRNA translation and gefitinib resistance in cancer.Cell Reports.2023, 42(7).

References

– Yee NS, et al. Targeting developmental regulators of zebrafish exocrine pancreas as a therapeutic approach in human pancreatic cancer. Biol Open. 2012;1(4):295-307.

CAS Number

– 577784-91-9

Molecular Weight

– C19H15Cl2N3O2S2

Compound Purity

– 0.981

SMILES

– Cc1c(sc2ccc(Cl)cc12)-c1cc(NS(=O)(=O)c2ccccc2Cl)n(C)n1

Pathway

– Cell Cycle/Checkpoint|||DNA Damage/DNA Repair

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.