UNC926

SKU T4012-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 48 CAD through 634 CAD

Products Details

Product Description

– UNC926 (UNC-926) inhibits L3MBTL1 (IC50: 3.9 μM). UNC926 also exhibits a low micromolar affinity for L3MBTL3. UNC926 inhibits binding of the 3xMBT domain to H4K20me1. It selectively and dose-dependently inhibits the L3MBTL13xMBT-H4K20me1 interaction. UNC926 has not an effect on the binding of 53BP1 to H4K20me1.

Web ID

– T4012

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C16H21BrN2O

References

– Herold, J., James, L., Korboukh, V., Gao, C., Coil, K., & Bua, D. et al. (2012). Structure–activity relationships of methyl-lysine reader antagonists. Med. Chem. Commun., 3(1), 45-51. doi: 10.1039/c1md00195g.

CAS Number

– 1184136-10-4

Molecular Weight

– C16H21BrN2O

Compound Purity

– 0.9722

SMILES

– Brc1cccc(c1)C(=O)N1CCC(CC1)N1CCCC1

Pathway

– Chromatin/Epigenetic

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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