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Hydroxyzine (pamoate)
$50 – $128
Products Details
Product Description
– Hydroxyzine pamoate is a histamine receptor H1 antagonist.
Web ID
– HY-B0895
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C44H43ClN2O8
References
– [1]Minogiannis, P., et al., Hydroxyzine inhibits neurogenic bladder mast cell activation. Int J Immunopharmacol, 1998. 20(10): p. 553-63.|[2]Dimitriadou, V., X. Pang, and T.C. Theoharides, Hydroxyzine inhibits experimental allergic encephalomyelitis (EAE) and associated brain mast cell activation. Int J Immunopharmacol, 2000. 22(9): p. 673-84.|[3]Kan, W.M., et al., Effect of hydroxyzine on the transport of etoposide in rat small intestine. Anticancer Drugs, 2001. 12(3): p. 267-73.|[4]Morichi, R. and G. Pepeu, A study of the influence of hydroxyzine and diazepam on morphine antinociceptoion in the rat. Pain, 1979. 7(2): p. 173-80.
CAS Number
– 10246-75-0
Molecular Weight
– 763.27
Compound Purity
– 99.84
SMILES
– O=C(C1=C(O)C(CC2=C3C=CC=CC3=CC(C(O)=O)=C2O)=C4C=CC=CC4=C1)O.ClC5=CC=C(C(N6CCN(CCOCCO)CC6)C7=CC=CC=C7)C=C5
Clinical Information
– Launched
Research Area
– Inflammation/Immunology; Endocrinology
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– Histamine Receptor
Isoform
– H1 Receptor
Pathway
– GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
