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QL-X-138

SKU T38960-1 mg Category Small Compound Brand: TargetMol

Price range: 309 CAD through 1,139 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 10 mg 5 mg

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Products Details

Product Description

– QL-X-138 is a potent and selective BTK and MNK dual kinase inhibitor that binds covalently to BTK and non-covalently to MNK. The IC50 values of QL-X-138 are 9.4 nM for BTK, 107.4 nM for MNK1, 26 nM for MNK2, and 3.5 μM against Dengue 2. QL-X-138 is used in the study of B-cell malignancies and B-cell malignant tumors.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T38960

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H19N5O2

References

– Wu H, et, al. Discovery of a BTK/MNK dual inhibitor for lymphoma and leukemia. Leukemia. 2016 Jan;30(1):173-81.

CAS Number

– 1469988-63-3

Molecular Weight

– C25H19N5O2

Compound Purity

– 0.995

SMILES

– O=C1N(C2=C3C(=NC=C2C=C1)C=CC(=C3)C=4C=NNC4)C5=CC(NC(C=C)=O)=C(C)C=C5

Pathway

– Tyrosine Kinase/Adaptors|||MAPK|||Angiogenesis|||Microbiology/Virology

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.