Sparstolonin B

SKU T38261-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 48 CAD through 602 CAD

Products Details

Product Description

– Sparstolonin B, a selective TLR2 and TLR4 antagonist, is an isocoumarin compound isolated from the tubers of Sparganium stoloniferum and Scirpus yagara with anti-HIV, anticancer, antitumour and anti-inflammatory activities, inhibits selective Toll-like receptors, inhibits free fatty acids It inhibits selective Toll-like receptors, inhibits free fatty acid palmitate-induced chondrocyte inflammation and attenuates post-traumatic arthritis in obese mice, and inhibits lipopolysaccharide-induced inflammation in 3T3-L1 adipocytes, which can be used for validation and mammary carcinoma studies.

Web ID

– T38261

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H8O5

References

– Liang Q, et al. Characterization of sparstolonin B, a Chinese herb-derived compound, as a selective Toll-like receptor antagonist with potent anti-inflammatory properties. J Biol Chem. 2011;286(30):26470-26479.

CAS Number

– 1259330-61-4

Molecular Weight

– C15H8O5

Compound Purity

– 0.9954

SMILES

– Oc1ccc2oc3ccc(O)c4c3c(coc4=O)c2c1

Pathway

– Immunology/Inflammation|||Proteases/Proteasome|||Microbiology/Virology

Product type

– Natural Product

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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