13(S)-HpODE

SKU T37393-1 mg Category Brand:

378 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Products Details

Product Description

– 13(S)-HpODE, a metabolite present in potato and Homo sapiens, is the (S)-enantiomer of 13-HpODE, a fatty acid containing a peroxy group, IL-13/13(S)HpODE stimulates MAO-A-mediated intracellular ROS generation and induction of p53 as well as p21 during apoptosis of A549 cancer cells and promotes apoptosis of HCT116 and CCF52 cells by upregulating p53 and p21 expression promoted apoptosis in HCT116 and CCF52 cells, constituting the IL-13 > 15-LO > 13(S)HpODE > PPARγ > MAO-A > ROS > p53 > p21 axis.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T37393

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H32O4

References

– Gardner, H.W. Soybean lipoxygenase-1 enzymically forms both (9S)- and (13S)-hydroperoxides from linoleic acid by a pH-dependent mechanism Biochim. Biophys. Acta 1001(3), 274-281 (1989).

CAS Number

– 33964-75-9

Molecular Weight

– C18H32O4

SMILES

– [C@@H](/C=C/C=CCCCCCCCC(O)=O)(CCCCC)OO

Pathway

– Neuroscience|||Apoptosis|||Metabolism

Product type

– Natural Product

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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For Research Use Only. All Immunomart products are sold strictly for laboratory research use only (RUO). Not for human or veterinary consumption, therapeutic, or diagnostic use.