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LSN3106729 hydrochloride

SKU T36967-1 mL * 10 mM (in DMSO) Category PROTAC Brand: TargetMol

Price range: 466 CAD through 2,976 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– LSN3106729 hydrochloride, the metabolite of Abemaciclib, is a CDK inhibitor with antitumor activity. LSN3106729 hydrochloride and a CRBN ligand have been used to design PROTAC CDK4/6 degrader[1].

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T36967

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H29ClF2N8O

References

– Edward S. Kim, et al. Abemaciclib in Combination with Single-Agent Options in Patients with Stage IV Non-Small Cell Lung Cancer: A Phase Ib Study.

CAS Number

– 2704316-82-3

Molecular Weight

– C25H29ClF2N8O

SMILES

– Cl.FC=1C=NC(=NC1C=2C=C(F)C=3N=C(N(C3C2)C(C)C)CO)NC4=NC=C(C=C4)CN5CCNCC5

Pathway

– Others

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.