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Combretastatin A-1

SKU T36848-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 56 CAD through 142 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)

Clear

Products Details

Product Description

– Combretastatin A-1 is a potent microtubule inhibitor with anti-tumour and anti-vascular activity, acting through microtubule protein depolymerisation-mediated inactivation of AKT to inhibit the Wnt/β-catenin pathway, and can be used to study hepatocellular carcinoma.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T36848

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H20O6

References

– Pettit GR, et al. Isolation, structure, and synthesis of combretastatins A-1 and B-1, potent new inhibitors of microtubule assembly, derived from Combretum caffrum. J Nat Prod. Jan-Feb 1987;50(1):119-31.

CAS Number

– 109971-63-3

Molecular Weight

– C18H20O6

Compound Purity

– 0.9749

SMILES

– COc1ccc(C=C/c2cc(OC)c(OC)c(OC)c2)c(O)c1O

Pathway

– Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.