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PDE4B-IN-2

SKU T36832-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 50 CAD through 2,016 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg 500 mg

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Products Details

Product Description

– PDE4B-IN-2 (A 33) is an orally active and selective PDE4B inhibitor with an IC50 of 15 nM. PDE4B-IN-2 inhibits PDE4D (IC50=1.7 µM). PDE4B-IN-2 exhibits potent anti-inflammatory effects.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T36832

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H18ClN3O2S

Citations

– 1. Sun R, Han M, Lin Y, et al.Inhibition of PDE4B ameliorates cognitive defects in the model of alcoholic dementia in 3× Tg-AD mice via PDE4B/cAMP/PKA signaling.International Journal of Neuropsychopharmacology.2025: pyaf009.

References

– Kenji Naganuma, et al. Discovery of selective PDE4B inhibitors. Bioorg Med Chem Lett. 2009 Jun 15;19(12):3174-6.

CAS Number

– 915082-52-9

Molecular Weight

– C19H18ClN3O2S

Compound Purity

– 0.9937

SMILES

– CCc1c(C)nc(nc1Nc1ccc(CC(O)=O)cc1)-c1ccc(Cl)s1

Pathway

– Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.