MTI-31

SKU T35343-1 mg Category Brand:

Price range: 315 CAD through 3,488 CAD

Products Details

Product Description

– MTI-31 (LXI-15029) is a potent, orally active, and highly selective inhibitor of mTORC1 and mTORC2, exhibiting a Kd of 0.20 nM for mTOR and >5,000-fold selectivity over PIK3CA, PIK3CB, and PIK3G in binding assays, with an IC50 of 39 nM for mTOR in a LANCE assay of mTOR substrate phosphorylation with 100 μM ATP [1].

Web ID

– T35343

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C26H30N6O3

References

– Jianchang Qian, et al. Oncotarget . 2016 Oct 11;7(41):67071-67086.

CAS Number

– 1567915-38-1

Molecular Weight

– C26H30N6O3

Compound Purity

– 0.9997

SMILES

– CNC(=O)c1cccc(c1)-c1ccc2c(nc(nc2n1)N1CCOC[C@@H]1C)N1C2CCC1COC2

Target

– Others

Pathway

– PI3K/Akt/mTOR signaling

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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