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Cinobufagin

SKU T3432-1 mL * 10 mM (in DMSO) Category Natural Product Brand: TargetMol

Price range: 70 CAD through 1,696 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg 500 mg

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Products Details

Product Description

– Cinobufagin (Cinobufagine) is a selective Na+/K+-ATPase inhibitor. The activity of Cinobufagin is same as ouabain.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T3432

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C26H34O6

Citations

– 1. Yang W, Sun X, Liu S, et al.TLR8 agonist Motolimod-induced inflammatory death for treatment of acute myeloid leukemia.Biomedicine & Pharmacotherapy.2023, 163: 114759. 2. Chen S, Li M, Xue C, et al.Validation of Core Ingredients and Molecular Mechanism of Cinobufotalin Injection Against Liver Cancer.Drug Design, Development and Therapy.2024, 18: 1321-1338. 3. Li X, Li X, Xiang C, et al.Starvation-induced phosphorylation activates gasdermin A to initiate pyroptosis.Cell Reports.2024, 43(9).

References

– Jiun-Yih Yeh, et al. Effects of bufalin and cinobufagin on the proliferation of androgen dependent and independent prostate cancer cells. The Prostate Volume 54, Issue 2, pages 112–124, 1 February 2003

CAS Number

– 470-37-1

Molecular Weight

– C26H34O6

Compound Purity

– 0.9997

SMILES

– CC(=O)[C@H]1[C@H]2O[C@]22[C@@H]3CC[C@@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]2(C)[C@H]1c1ccc(=O)oc1

Pathway

– Autophagy|||Apoptosis|||Membrane transporter/Ion channel

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.