Download Files:
Panduratin A
352 CAD
Only 1000 item(s) left in stock.
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– Panduratin A is a natural chalcone derivative with inhibitory activity against MMP-9 in human oral epidermoid carcinoma KB cells; inhibitory activity against the NS3 protease of DENV-2 (Ki=25 μM); significant cytotoxicity against human androgen-independent prostate cancer cells PC-3 and DU-145; and also able to activate the LKB1-AMPK- PPARα /δ signaling pathway and enhance the oxidative capacity of myocyte mitochondria.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T33875
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C26H30O4
References
– Hariono M, Choi SB, Roslim RF, Nawi MS, Tan ML, Kamarulzaman EE, Mohamed N, Yusof R, Othman S, Abd Rahman N, Othman R, Wahab HA. Thioguanine-based DENV-2 NS2B/NS3 protease inhibitors: Virtual screening, synthesis, biological evaluation and molecular modelling. PLoS One. 2019 Jan 24;14(1):e0210869. doi: 10.1371/journal.pone.0210869. eCollection 2019. PubMed PMID: 30677071; PubMed Central PMCID: PMC6345492.
CAS Number
– 89837-52-5
Molecular Weight
– C26H30O4
SMILES
– C(=O)([C@H]1[C@@H](CC=C(C)[C@H]1CC=C(C)C)C2=CC=CC=C2)C3=C(O)C=C(OC)C=C3O
Pathway
– Metabolism|||Microbiology/Virology|||Proteases/Proteasome|||Chromatin/Epigenetic|||DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
1000 in stock
1000 in stock
Proudly representing
150+ years of combined research-supply heritage
