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Jervine
Price range: 102 CAD through 2,432 CAD
Products Details
Product Description
– The biological activity of Jervine (Jerwiny) is mediated via its interaction with the 7 passes transmembrane protein Smoothened. Jervine binds with and inhibits smoothened, which is an integral part of the Hedgehog signaling pathways. With smoothened inhibited, the GLI1 transcription cannot be activated and Hedgehog target genes cannot be transcribed.
Web ID
– T3363
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C27H39NO3
References
– ten Berge D, et al. Development. 2001, 128(15):2929-38.
CAS Number
– 469-59-0
Molecular Weight
– C27H39NO3
Compound Purity
– 0.996
SMILES
– [H][C@@]12NC[C@@H](C)C[C@H]1O[C@]1(CC[C@]3([H])C(C(=O)[C@@]4([H])[C@@]3([H])CC=C3C[C@@H](O)CC[C@]43C)=C1C)[C@@H]2C
Pathway
– Stem Cells|||GPCR/G Protein
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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