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ML277

SKU T3303-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 54 CAD through 773 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– ML277 (CID-53347902) was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T3303

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H25N3O4S2

References

– Mattmann ME, Yu H, Lin Z, et al. Identification of (R)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide, ML277, as a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator. Bioorg Med Chem Lett. 2012;22(18):5936-5941. doi:10.1016/j.bmcl.2012.07.060

CAS Number

– 1401242-74-7

Molecular Weight

– C23H25N3O4S2

Compound Purity

– 0.9997

SMILES

– COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2ccc(C)cc2)n1

Target

– COX|||Bcl-2 Family|||Caspase|||p53

Pathway

– Membrane transporter/Ion channel

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.