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Ponicidin

SKU T2S1975-1 mL * 10 mM (in DMSO) Category Natural Product Brand: TargetMol

Price range: 102 CAD through 350 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– Ponicidin (Rubescensine B) is a diterpenoid derived from Rabdosia rubescens that exhibits immunoregulatory, anti-inflammatory, anti-viral, and anti-cancer activity. Ponicidin induces apoptosis of gastric carcinoma cells, decreases the phosphorylation of JAK2 and STAT3, and shows no effect on the protein levels of JAK2 and STAT3.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T2S1975

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H26O6

References

– Xiaodan Liu, et al. Apoptosis inducing effect of ponicidin in leukemia K562 cells and its mechanisms of action. Zhongguo Zhong Yao Za Zhi. 2010 Aug;35(16):2161-5.

CAS Number

– 52617-37-5

Molecular Weight

– C20H26O6

Compound Purity

– 0.9985

SMILES

– [H][C@]12CC[C@]3([H])[C@]4(C(=O)C1=C)[C@@]2([H])O[C@@]1([H])O[C@]4(O)[C@@H](O)[C@]2([H])C(C)(C)CC[C@H](O)C312

Pathway

– JAK/STAT signaling|||Stem Cells|||Angiogenesis|||Apoptosis|||Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.