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(E)-Cardamonin

SKU T2994-1 mL * 10 mM (in DMSO) Category Natural Product Brand: TargetMol

Price range: 48 CAD through 453 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 50 mg 500 mg

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Products Details

Product Description

– (E)-Cardamonin (Alpinetin chalcone) is a chalconoid that has been isolated from several plants including Alpinia katsumadai and Alpinia conchigera. It is a novel antagonist of hTRPA1 cation channel with an IC50 of 454 nM. It has received growing attention from the scientific community due to the expectations toward its benefits to human health.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T2994

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C16H14O4

Citations

– 1. He J, Zhou H, Meng J, et al. Cardamonin retards progression of autosomal dominant polycystic kidney disease via inhibiting renal cyst growth and interstitial fibrosis. Pharmacological Research. 2020: 104751

References

– Wang S, et al. Cardamonin, a Novel Antagonist of hTRPA1 Cation Channel, Reveals Therapeutic Mechanism of Pathological Pain. Molecules. 2016 Aug 29;21(9). pii: E1145.

CAS Number

– 19309-14-9

Molecular Weight

– C16H14O4

Compound Purity

– 0.9808

SMILES

– C(/C=C/C1=CC=CC=C1)(=O)C2=C(OC)C=C(O)C=C2O

Pathway

– Apoptosis|||Membrane transporter/Ion channel

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.