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Rotenone
67 CAD – 142 CADPrice range: 67 CAD through 142 CAD
Products Details
Product Description
– Rotenone (Rotocide) is a natural product and a botanical insecticide. Rotenone is a mitochondrial electron transport complex I inhibitor that promotes the production of reactive oxygen species in mitochondria and induces apoptosis.
Web ID
– T2970
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C23H22O6
Citations
– 1. Li Y, Sun H, Tian Z, et al. The determination of Plutella xylostella (L.) GSTs (PxGSTs) involved in the detoxification metabolism of Tolfenpyrad. Pest Management Science. 2020
2. Yi Y, Gao K, Lin P, et al. Staphylococcus aureus-Induced Necroptosis Promotes Mitochondrial Damage in Goat Endometrial Epithelial Cells. Animals. 2022, 12(17): 2218.
3. Zhang R, Fang J, Qi T, et al.Maternal aging increases offspring adult body size via transmission of donut-shaped mitochondria.Cell Research.2023: 1-14.
4. Ma W, Sun Y, Yan R, et al.OXCT1 functions as a succinyltransferase, contributing to hepatocellular carcinoma via succinylating LACTB.Molecular Cell.2023
5. Wang J, Chen J, Fan K, et al.Inhibition of Endoplasmic Reticulum Stress Cooperates with SLC7A11 to Promote Disulfidptosis and Suppress Tumor Growth upon Glucose Limitation.Advanced Science.2024: 2408789.
6. Ning X, Chen X, Li R, et al.Identification of a Novel Cuproptosis Inducer That Induces ER Stress and Oxidative Stress to Trigger Immunogenic Cell Death in Tumors.Free Radical Biology and Medicine.2025
7. Non-canonical hepatic androgen receptor mediates glucagon sensitivity in female mice through the PGC1α/ERRα/mitochondria axis
References
– Li N, et al. Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production. J Biol Chem. 2003 Mar 7;278(10):8516-25.
CAS Number
– 83-79-4
Molecular Weight
– C23H22O6
Compound Purity
– 0.9988
SMILES
– O=C1C=2C(=C3C(O[C@@H](C(C)=C)C3)=CC2)O[C@]4([C@@]1(C=5C(OC4)=CC(OC)=C(OC)C5)[H])[H]
Pathway
– Autophagy|||Apoptosis|||Metabolism
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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