VA-K-14 hydrochloride
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VA-K-14 hydrochloride

SKU T29087-1 mg Category Brand:

Price range: 86 CAD through 1,579 CAD

Products Details

Product Description

– VA-K-14 hydrochloride(VAK14 HCl) is a selective thyrotropin receptor (TSHR) antagonist (IC50= 12.3 μM) that inhibits TSHR stimulation by serum and monoclonal TSHR-stimulating antibodies from patients with GD and abrogates TSHR signaling.

Web ID

– T29087

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H16ClN3S

References

– Latif R, et al. TSH Receptor Signaling Abrogation by a Novel Small Molecule. Front Endocrinol (Lausanne). 2016;7:130.

CAS Number

– 1171341-19-7

Molecular Weight

– C18H16ClN3S

Compound Purity

– 0.9801

SMILES

– Cl.CNc1nc(cs1)-c1c([nH]c2ccccc12)-c1ccccc1

Pathway

– GPCR/G Protein

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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