Facinicline hydrochloride

SKU T28531-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 77 CAD through 699 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Products Details

Product Description

– Facinicline hydrochloride (RG3487) is both a novel nicotinic alpha-7 receptor (alpha7nAChR) partial agonist (Ki = 6 nM) and an antagonist of 5-HT3(Ki = 1.2 nM). Facinicline hydrochloride improves cognition and sensorimotor gating in rodents.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T28531

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H19ClN4O

References

– Boess F, et al. Use of early phenotypic in vivo markers to assess human relevance of an unusual rodent non-genotoxic carcinogen in vitro. Toxicology. 2017 Mar 15;379:48-61.

CAS Number

– 677305-02-1

Molecular Weight

– C15H19ClN4O

Compound Purity

– 0.9972

SMILES

– Cl.O=C(N[C@@H]1CN2CCC1CC2)c1n[nH]c2ccccc12

Pathway

– GPCR/G Protein|||Neuroscience

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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For Research Use Only. All Immunomart products are sold strictly for laboratory research use only (RUO). Not for human or veterinary consumption, therapeutic, or diagnostic use.