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Dehydrocostus Lactone

SKU T2833-1 mL * 10 mM (in DMSO) Category Natural Product Brand: TargetMol

Price range: 62 CAD through 1,262 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg 500 mg

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Products Details

Product Description

– Dehydrocostus Lactone ((-)-Dehydrocostus lactone) shows anti-inflammatory, anti-ulcer, immunomodulatory and anti-tumor properties.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T2833

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H18O2

Citations

– 1. Wu Y X, Jiang F J, Liu G, et al. Dehydrocostus Lactone Attenuates Methicillin-Resistant Staphylococcus aureus-Induced Inflammation and Acute Lung Injury via Modulating Macrophage Polarization. International Journal of Molecular Sciences. 2021, 22(18): 9754. 2. Xiong Y, Cui X, Zhou Y, et al. Dehydrocostus lactone inhibits BLM-induced pulmonary fibrosis and inflammation in mice via the JNK and p38 MAPK-mediated NF-κB signaling pathways. International Immunopharmacology. 2021, 98: 107780 3. Chen Y, Li R, Wang Z, et al. Dehydrocostus lactone inhibits NLRP3 inflammasome activation by blocking ASC oligomerization and prevents LPS-mediated inflammation in vivo. Cellular Immunology. 2020, 349: 104046 4. Nie Y, Wang Z, Chai G, et al. Dehydrocostus Lactone Suppresses LPS-induced Acute Lung Injury and Macrophage Activation through NF-κB Signaling Pathway Mediated by p38 MAPK and Akt. Molecules. 2019 Apr 17;24(8). pii: E1510.

References

– Dong GZ, et al. PhytOthers Res. 2015 May;29(5):680-6.

CAS Number

– 477-43-0

Molecular Weight

– C15H18O2

Compound Purity

– 0.9986

SMILES

– C=C1[C@@]2([C@@]3([C@](C(=C)C(=O)O3)(CCC(=C)[C@@]2(CC1)[H])[H])[H])[H]

Pathway

– NF-κB

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.