MMRi64
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MMRi64

SKU T28078-1 mg Category Brand:

Price range: 82 CAD through 2,320 CAD

Products Details

Product Description

– MMRi64 is a specific inhibitor of Mdm2-MdmX E3 ligase activity.MMRi64 potently induces p53 accumulation and apoptosis in the p53 pathway in leukemia/lymphoma cells, disrupts Mdm2-MdmX interactions, and downregulates Mdm2 and MdmX in leukemia cells.MMRi64 MMRi64 can be used in cancer research.

Web ID

– T28078

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H17Cl2N3O

References

– Wu W, et al. Targeting RING domains of Mdm2-MdmX E3 complex activates apoptotic arm of the p53 pathway in leukemia/lymphoma cells. Cell Death Dis. 2015;6(12):e2035.

CAS Number

– 430458-66-5

Molecular Weight

– C22H17Cl2N3O

Compound Purity

– 0.9961

SMILES

– C(NC1=CC(C)=CC=N1)(C2=C(O)C3=C(C=C2)C=CC=N3)C4=C(Cl)C(Cl)=CC=C4

Pathway

– Apoptosis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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