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JNJ-42253432

SKU T27683-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 114 CAD through 1,579 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– JNJ-42253432 is an oral active P2X7 antagonist capable of penetrating the central nervous system with a pKi value of 9.1 for rat and 7.9 for human P2X7 channels.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T27683

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C28H38N4O

References

– Brian Lord.et al.Pharmacology of a novel central nervous system-penetrant P2X7 antagonist JNJ-42253432.J Pharmacol Exp Ther. 2014 Dec;351(3):628-41.

CAS Number

– 1428327-35-8

Molecular Weight

– C28H38N4O

Compound Purity

– 0.9908

SMILES

– CN1CCc2c(C1)cccc2C(=O)NCC1(CCCCC1)N1CCN(CC1)c1ccccc1

Pathway

– Neuroscience|||Membrane transporter/Ion channel

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.