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Products Details
Product Description
– FR900359, a non-ribosomal cyclic peptide derived from the soil bacterium Chromobacterium oxysporum, is a macrocyclic Gq protein inhibitor that inhibits melanoma cell proliferation and can be used in studies of asthma, inflammation, and cancer.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T27387
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C49H75N7O15
References
– Reher R, Schamari I, Kehraus S, Annala S, Kuschak M, Schäberle T, Crüsemann M, Carlier A, Eberl L, Müller CE, Kostenis E, König GM. The endophyte Candidatus Burkholderia crenata of the TCM plant Ardisia crenata produces the selective Gq-inhibitor FR900359. Planta Med. 2016 Dec;81(S 01):S1-S381. PubMed PMID: 27975935.
CAS Number
– 107530-18-7
Molecular Weight
– C49H75N7O15
SMILES
– [C@@H](OC([C@@H](NC(CC)=O)[C@@H](C(C)C)O)=O)(C(C)C)[C@]1(C(=O)N(C)[C@@]([C@H](OC)C)(C(=O)O[C@H](C(C)C)[C@H](NC(C)=O)C(=O)O[C@H](CC2=CC=CC=C2)C(=O)N(C)C(=C)C(=O)N[C@@H](C)C(=O)N(C)[C@@H](C)C(=O)N1)[H])[H]
Pathway
– MAPK|||Apoptosis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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