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FTI-277 hydrochloride
Price range: 77 CAD through 1,269 CAD
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– FTI-277 hydrochloride (FTI 277 HCl) is an effective and specific farnesyltransferase (FTase) inhibitor (IC50: 500 pM); this selectivity is about 100-fold than the closely related GGTase I.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T2700
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C22H30ClN3O3S2
Citations
– 1. Sun Q, Xiong K, Yuan Y, et al Inhibiting fungal echinocandin resistance by small-molecule disruption of geranylgeranyltransferase type I activity. Antimicrobial Agents and Chemotherapy. 2020, 64(2).
References
– Lerner EC, et al. J Biol Chem. 1995, 270(45), 26802-26806.
CAS Number
– 180977-34-8
Molecular Weight
– C22H30ClN3O3S2
Compound Purity
– 0.9819
SMILES
– Cl.Cl.COC(=O)C(CCSC)NC(=O)c1ccc(NCC(N)CS)cc1-c1ccccc1
Pathway
– Metabolism|||Apoptosis|||MAPK|||GPCR/G Protein
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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