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BI-135585

SKU T26794-1 mg Category Small Compound Brand: TargetMol

Price range: 464 CAD through 3,488 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– BI-135585 is an orally active, selective and potent inhibitor of human 11β-hydroxysteroid dehydrogenase-1 (HSD1) for the study of type 2 diabetes.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T26794

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C28H32N2O4

References

– Freude S, Heise T, Woerle HJ, Jungnik A, Rauch T, Hamilton B, Schölch C, Huang F, Graefe-Mody U. Safety, pharmacokinetics and pharmacodynamics of BI 135585, a selective 11β-hydroxysteroid dehydrogenase-1 (HSD1) inhibitor in humans: liver and adipose tissue 11β-HSD1 inhibition after acute and multiple administrations over 2 weeks. Diabetes Obes Metab. 2016 May;18(5):483-90. doi: 10.1111/dom.12635. PubMed PMID: 26799632.

CAS Number

– 1114561-85-1

Molecular Weight

– C28H32N2O4

Compound Purity

– 0.9957

SMILES

– C(C(C)(C)O)[C@]1(OC(=O)N([C@@H](C)C2=CC=C(C=C2)C3=CC(=O)N(C)C=C3)CC1)C4=CC=CC=C4

Pathway

– Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.