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PD173074
Price range: 58 CAD through 1,102 CAD
Products Details
Product Description
– PD173074 is an effective FGFR1 inhibitor (IC50: 25 nM) and also inhibits VEGFR2 (IC50: 100-200 nM) in cell-free assays. The selectivity is higher ~1000-fold for FGFR1 than PDGFR and c-Src.
Web ID
– T2642
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C28H41N7O3
Citations
– 1. Huang G K, Huang C C, Kang C H, et al.Genetic Interference of FGFR3 Impedes Invasion of Upper Tract Urothelial Carcinoma Cells by Alleviating RAS/MAPK Signal Activity.International Journal of Molecular Sciences.2023, 24(2): 1776.
References
– Mohammadi M, et al. EMBO J, 1998, 17(20), 5896-5904.
CAS Number
– 219580-11-7
Molecular Weight
– C28H41N7O3
Compound Purity
– 0.9815
SMILES
– CCN(CC)CCCCNc1ncc2cc(c(NC(=O)NC(C)(C)C)nc2n1)-c1cc(OC)cc(OC)c1
Pathway
– Tyrosine Kinase/Adaptors|||Apoptosis|||JAK/STAT signaling|||Angiogenesis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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