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Nolatrexed dihydrochloride
Price range: 62 CAD through 366 CAD
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– Nolatrexed dihydrochloride (Thymitaq) is the dihydrochloride salt of nolatrexed, a water-soluble lipophilic quinazoline folate analog with antineoplastic activity. Nolatrexed occupies the folate binding site of thymidylate synthase, resulting in inhibition of thymidylate synthase activity and thymine nucleotide synthesis with subsequent inhibition of DNA replication, DNA damage, S-phase cell cycle arrest, and caspase-dependent apoptosis. This agent also exhibits radiosensitizing activity.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T2627
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C14H14Cl2N4OS
References
– Hughes AN, et al. Br J Y. 2000 May;82(9):1519-27.
CAS Number
– 152946-68-4
Molecular Weight
– C14H14Cl2N4OS
Compound Purity
– 0.9702
SMILES
– Cl.Cl.Cc1ccc2[nH]c(N)nc(=O)c2c1Sc1ccncc1
Pathway
– DNA Damage/DNA Repair|||Cell Cycle/Checkpoint
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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