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SKA-111
Price range: 102 CAD through 3,440 CAD
Products Details
Product Description
– SKA-111 is a selective calcium-activated potassium phannel (potassium phannel ) KCa3.1 activator that induces membrane hyperpolarization in porcine endothelial cells.SKA-111 binds to the interface between the CaM N-valve and the S4-S5 junction and ameliorates Bradykinin-induced dilation of coronary arteries in the isolated rat heart, which can be used for the study of cardiovascular diseases. study of cardiovascular diseases.
Web ID
– T24799
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C12H10N2S
References
– Oliván-Viguera A, et al. Vascular Reactivity Profile of Novel KCa 3.1-Selective Positive-Gating Modulators in the Coronary Vascular Bed. Basic Clin Pharmacol Toxicol. 2016 Aug;119(2):184-92.
CAS Number
– 1369170-24-0
Molecular Weight
– C12H10N2S
Compound Purity
– 0.9979
SMILES
– NC1=NC=2C=3C(C(C)=CC2S1)=CC=CC3
Pathway
– Membrane transporter/Ion channel
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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