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JTV-519

SKU T24239-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 88 CAD through 2,000 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg 500 mg

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Products Details

Product Description

– JTV-519 is a Ca2+-dependent blocker and prevents abnormal Ca(2+) leak from the sarcoplasmic reticulum in the ischemic heart and skeletal muscle (SkM) by stabilizing the ryanodine receptors.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T24239

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H33ClN2O2S

References

– Darcy YL, Diaz-Sylvester PL, Copello JA. K201 (JTV519) is a Ca2+-Dependent Blocker of SERCA and a Partial Agonist of Ryanodine Receptors in Striated Muscle. Mol Pharmacol. 2016 Aug;90(2):106-15.

CAS Number

– 1038410-88-6

Molecular Weight

– C25H33ClN2O2S

Compound Purity

– 0.998

SMILES

– Cl.O=C(N1CC2=CC(OC)=CC=C2SCC1)CCN3CCC(CC=4C=CC=CC4)CC3

Pathway

– Membrane transporter/Ion channel|||Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.