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HTH-01-091

SKU T24152-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 474 CAD through 4,000 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– HTH-01-091 is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor (IC50: 10.5 nM) that also inhibits PIM1/2/3, RIPK2, DYRK3, smMLCK, and CLK2. It can be used to study breast cancer.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T24152

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C26H28Cl2N4O2

References

– Huang HT, et al. MELK is not necessary for the proliferation of basal-like breast cancer cells. Elife. 2017;6:e26693.

CAS Number

– 2000209-42-5

Molecular Weight

– C26H28Cl2N4O2

Compound Purity

– 0.984

SMILES

– O=C1N(C2=C3C(=NC=C2CN1)C=CC(=C3)C4=CC(Cl)=C(O)C(Cl)=C4)[C@@H]5CC[C@@H](CN(C)C)CC5

Pathway

– JAK/STAT signaling|||PI3K/Akt/mTOR signaling|||Cell Cycle/Checkpoint|||Apoptosis|||Metabolism|||Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors|||NF-κB

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.