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PP121

SKU T2415-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 82 CAD through 581 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– PP-121 is a multi-targeted inhibitor of PDGFR (IC50: 2 nM), Hck (IC50: 8 nM), mTOR (IC50: 10 nM), VEGFR2(IC50: 12 nM), Src (IC50: 14 nM) and Abl (IC50: 18 nM), also inhibits DNA-PK (IC50: 60 nM).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T2415

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H17N7

Citations

– 1. Zhou D, Yang S, Yan H, et al. SC75741, a novel c-Abl inhibitor, promotes the clearance of TDP25 aggregates via ATG5-dependent autophagy pathway. Frontiers in Pharmacology. 2021: 2891.

References

– Apsel B, et al. Nat Chem Biol, 2008, 4(11), 691-699.

CAS Number

– 1092788-83-4

Molecular Weight

– C17H17N7

Compound Purity

– 0.9967

SMILES

– Nc1ncnc2n(nc(-c3cnc4[nH]ccc4c3)c12)C1CCCC1

Pathway

– Apoptosis|||Angiogenesis|||PI3K/Akt/mTOR signaling|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.