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ABC1183
Price range: 56 CAD through 93 CAD
Products Details
Product Description
– ABC1183 is a novel diaminothiazole that inhibits GSK3α, GSK3β and CDK9. ABC1183 inhibits the growth of a numerous cancer cell lines by decreasing cell survival by inducing G2/M arrest and through altering GSK3, glycogen synthetase, β-catenin phosphorylation and MCL1 expression,and is orally active.
Web ID
– T23601
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C18H14N4OS
References
– Schrecengost RS, et al. In Vitro and In Vivo Antitumor and Anti-Inflammatory Capabilities of the Novel GSK3 and CDK9 Inhibitor ABC1183. J Pharmacol Exp Ther. 2018 Apr;365(1):107-116.
CAS Number
– 1042735-18-1
Molecular Weight
– C18H14N4OS
Compound Purity
– 0.9853
SMILES
– Cc1ccc(Nc2nc(N)c(s2)C(=O)c2ccc(cc2)C#N)cc1
Pathway
– Cell Cycle/Checkpoint|||Stem Cells|||PI3K/Akt/mTOR signaling
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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