Download Files:

PF-431396

SKU T2314-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 80 CAD through 1,054 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 5 mg 50 mg

Clear

Products Details

Product Description

– PF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T2314

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H21F3N6O3S

Citations

– 1. Xu H, Tan M, Hou G Q, et al.Blockade of DDR1/PYK2/ERK signaling suggesting SH2 superbinder as a novel autophagy inhibitor for pancreatic cancer.Cell Death & Disease.2023, 14(12): 811.

References

– Han S, et al. J Biol Chem. 2009, 284(19), 13193-13201.

CAS Number

– 717906-29-1

Molecular Weight

– C22H21F3N6O3S

Compound Purity

– 0.9883

SMILES

– CN(c1ccccc1CNc1nc(Nc2ccc3NC(=O)Cc3c2)ncc1C(F)(F)F)S(C)(=O)=O

Pathway

– Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling|||Angiogenesis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.