GW 583340 dihydrochloride
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GW 583340 dihydrochloride

SKU T22827-1 mg Category Brand:

Price range: 113  USD through 1,270  USD

Products Details

Product Description

– GW 583340 dihydrochloride is a potent and orally available dual EGFR/ErbB2 (epidermal growth factor receptor/tyrosine kinase) inhibitor and is capable of reversing ABCG2- and ABCB1-mediated resistance.GW 583340 dihydrochloride selectively inhibits the growth of human tumor cells overexpressing EGFR and ErbB2, selectively inhibits the growth of human tumor cells overexpressing EGFR and ErbB2, and inhibits 80% of tumor growth in a mouse xenograft model, with potential anticancer activity.

Web ID

– T22827

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C28H27Cl3FN5O3S2

CAS Number

– 1173023-85-2

Molecular Weight

– C28H27Cl3FN5O3S2

Compound Purity

– 0.988

SMILES

– O=S(C)(CCNCC1=NC(C2=CC3=C(NC4=CC=C(C(Cl)=C4)OCC5=CC(F)=CC=C5)N=CN=C3C=C2)=CS1)=O.Cl.Cl

Pathway

– Tyrosine Kinase/Adaptors|||Angiogenesis|||JAK/STAT signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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